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FDA strengthens canagliflozin and dapagliflozin kidney warnings

FDA has strengthened existing warnings about the risk of acute kidney injury associated with canagliflozin and dapagliflozin

FDA approves canagliflozin/metformin combo as first-line therapy

The fixed-dose combination can be prescribed in type 2 diabetes patients why may benefit from dual therapy

FDA adds warning about amputation risk with canagliflozin

The SGLT2 inhibitor has been associated with a two-fold risk for leg and foot amputations in a clinical trial

FDA: Metformin safe for some patients with renal impairment

FDA has expanded the labeling of diabetes medications that contain metformin to include patients with mild to moderate renal impairment

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