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Autoimmune disease

An immunologic disorder that results in the production of antibodies that react against an individual's own cells or cell products. Type 1 diabetes is often associated with autoantibody production, resulting in the destruction of beta-cells of the pancreas.


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Evidence of Islet Cell Autoimmunity in Elderly Patients With Type 2 Diabetes

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Pietropaolo M, Barinas-Mitchell E, Pietropaolo SL, Kuller LH, Trucco M. Evidence of Islet Cell Autoimmunity in Elderly Patients With Type 2 Diabetes. Diabetes. 2000;49:32-38. In light of an occurring growth of elderly people affected by type 2 diabetes and recent observations indicating that type 2 diabetes may be a disease of the innate immune system, we evaluated whether signs of islet cell autoimmunity are associated with an abnormal glucose control, the presence of insulin requirement, or an activation of the acute-phase response in older individuals with type 2 diabetes.



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Type 1 Diabetes Classification & Diagnosis