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Gemfibrozil

An oral medication of the fibrate class, it is mainly used with dietary changes (restriction of cholesterol and fat intake) to reduce the amount of cholesterol and triglycerides (fatty substances) in blood. Like other fibrates, fenofibrate acts on PPAR-al
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Insulin Resistance and Cardiovascular Events With Low HDL Cholesterol. The Veterans Affairs HDL Intervention Trial (VA-HIT)

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Robins SJ, Bloomfield Rubins H, Faas FH, et al. Insulin Resistance and Cardiovascular Events With Low HDL Cholesterol. The Veterans Affairs HDL Intervention Trial (VA-HIT). Diabetes Care. 2003;26:1513-1517. To assess the effect of insulin resistance and the benefit of the fibrate, gemfibrozil, on the incidence of major cardiovascular events in subjects with low HDL cholesterol and a broad range of triglyceride values who participated in the Veterans Affairs High Density Lipoprotein Intervention Trial (VA-HIT).



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Improvement of Lipid Profiles: Morbidity and Mortality Improvement of Lipid Profiles in Patients With Diabetes Reduces Cardiovascular Morbidity and Mortality
ACP Guidelines on Management of Dyslipidemia in Type 2 Diabetes
IDF Type 2 Diabetes Guidelines CVD Risk Reduction Treatment | NDEI