Click here for slides on this topic


Homocysteine

A metabolite of the amino acid methionine; chronically elevated blood levels of homocysteine are linked to atherosclerosis, probably through damage to the endothelium.


The following content matched the glossary term: Homocysteine

Clinical Insights in Diabetes Newsletter Archive

Top

Clinical Insights® in Diabetes Newsletter Archive

Homocysteine lowering with folic acid and B vitamins in vascular disease

Top

Lonn E, Yusuf S, Arnold MJ, et al. Homocysteine lowering with folic acid and B vitamins in vascular disease. N Engl J Med. 2006;354:1567-1577. In observational studies, lower homocysteine levels are associated with lower rates of coronary heart disease and stroke. Folic acid and vitamins B6 and B12 lower homocysteine levels.

Homocysteine concentrations in type 2 diabetic patients with silent myocardial ischemia; A predictive marker

Top

Tarkun I, Cetinarslan B, Canturk Z, Tarkun P, Acdiken A, Lu B. Homocysteine concentrations in type 2 diabetic patients with silent myocardial ischemia; A predictive marker. J Diabetes and Its Complications. 2004;18:165-168. Silent myocardial ischemia (SMI) is a frequent finding among diabetic patients. There are very few data on the relationship between homocysteine, which is a novel cardiovascular risk factor, and SMI in diabetic patients.

The Metabolic Response of Subjects with Type 2 Diabetes to a High-Protein, Weight-Maintenance Diet

Top

Nuttall FQ, Gannon MC, Saeed A, Jordan K, Hoover H. The Metabolic Response of Subjects with Type 2 Diabetes to a High-Protein, Weight-Maintenance Diet. J Clin Endocrinol Metab. 2003;88:3577-3583. In a randomized, crossover 5-week study design, we recently reported that a weight-maintaining diet in which the percentage of total food energy as protein was increased from 15%-30% resulted in a decrease in postprandial glucose and glycohemoglobin in people with untreated type 2 diabetes without a significant change in insulin.

An Elevated Homocysteine Level May Be a Risk Factor for Diabetic Retinopathy

Top

Hoogeveen EK, Kostense PJ, Eysink PED, et al. Hyperhomocysteinemia is associated with the presence of retinopathy in type 2 diabetes: The Hoorn study. Arch Intern Med. 2000;160:2984-2990. OBJECTIVE: To study the association between the homocysteine level and retinopathy among subjects with and without DM.



Slide Library Results

Search Results for: Homocysteine Slides Found: 4
Meta-Analysis: Risk for New-Onset Diabetes and CV Events with Intensive- Vs Moderate Dose Statins
Meta-Analysis: New-Onset Diabetes and CV Events With Intensive- Vs Moderate-Dose Statins
Meta-Analysis: New-Onset Diabetes With Intensive- Vs Moderate-Dose Statins
Meta-Analysis: CV Events With Intensive- Vs Moderate-Dose Statins