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Pancreas

A mixed exocrine and endocrine organ located in the abdomen. The exocrine portion of the gland makes digestive enzymes that are secreted into the gastrointestinal track in response to feeding. The endocrine pancreas is contained in the Islets of Langerhans, which contain cells that make insulin and glucagon, two main regulators of blood glucose levels.


The following content matched the glossary term: Pancreas

Incretin based drugs and risk of acute pancreatitis in patients with type 2 diabetes: cohort study

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Faillie J-L, Azoulay L, Patenaude V, Hillaire-Buys D, Suissa S. Incretin based drugs and risk of acute pancreatitis in patients with type 2 diabetes: cohort study. BMJ. 2014;348:g2780. doi 10.1136/bmj.g2780.

β-cell function preservation after 3.5 years of intensive diabetes therapy

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Harrison LB, Adams Huet B, Raskin P, Lingvay I. Beta cell function preservation after 3.5 years of intensive diabetes therapy. Diabetes Care. 2012;35(7):1406-1412. To assess beta-cell function preservation after 3.5 years of intensive therapy with insulin plus metformin (INS group) versus triple oral therapy (TOT group) with metformin, glyburide, and pioglitazone.

DPPOS: Effect of Regression from Prediabetes to NGR on Long-term Diabetes Risk Reduction

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Continuous coverage of ADA 2012. Perreault L, Pan Q, Mather KJ, et al; for the Diabetes Prevention Program Research Group. DPPOS: Effect of Regression from Prediabetes to NGR on Long-term Diabetes Risk Reduction. Lancet. 2012;379(9833):2243-2251. This report sought to quantify and predict diabetes risk reduction during the long-term follow-up to the Diabetes Prevention Program (DPP), the Diabetes Prevention Program Outcomes Study (DPPOS).

Diabetes and cause-specific mortality in a prospective cohort of one million U.S. adults

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Campbell PT, Newton CC, Patel AV, Jacobs EJ, Gapstur SM. Diabetes and cause specific mortality in a prospective cohort of one million U.S. adults. Diabetes Care. 2012 June 14. [Epub ahead of print] Diabetes is a major predictor of death from heart disease and stroke; its impact on nonvascular mortality, including specific cancers, is less understood.

Glucagon-like peptide analogues for type 2 diabetes mellitus

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Shyangdan DS, Royle P, Clar C, Sharma P, Waugh N, Snaith A. Glucagon-like peptide analogues for type 2 diabetes mellitus. Cochrane Database Syst Rev. 2011 Oct 5;(10):CD006423. Glucagon-like peptide analogues are a new class of drugs used in the treatment of type 2 diabetes that mimic the endogenous hormone glucagon-like peptide 1 (GLP-1). GLP-1 is an incretin, a gastrointestinal hormone that is released into the circulation in response to ingested nutrients.

From Theory to Clinical Practice in the Use of GLP-1 Receptor Agonists and DPP-4 Inhibitors Therapy

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Dicembrini I, Pala L, Rotella CM. From Theory to Clinical Practice in the Use of GLP-1 Receptor Agonists and DPP-4 Inhibitors Therapy. Exp Diabetes Res. 2011;2011:898913. Epub 2011 Jun 23. Promoting long-term adherence to lifestyle modification and choice of antidiabetic agent with low hypoglycemia risk profile and positive weight profile could be the most effective strategy in achieving sustained glycemic control and in reducing comorbidities.

Association between diagnosed diabetes and self-reported cancer among u.s. Adults: findings from the 2009 behavioral risk factor surveillance system

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Li C, Balluz LS, Ford ES, Okoro CA, Tsai J, Zhao G. Association between diagnosed diabetes and self-reported cancer among u.s. Adults: findings from the 2009 behavioral risk factor surveillance system. Diabetes Care. 2011;34(6):1365-8. OBJECTIVE To assess the association between diagnosed diabetes and self-reported cancer among U.S. adults.

The relationship between {beta}-cell function and glycated hemoglobin: results from the Veterans Administration Genetic Epidemiology study

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The relationship between beta cell function and glycated hemoglobin results from the Veterans Administration Genetic Epidemiology studyKanat M, Winnier D, Norton L, Arar N, Jenkinson C, Defronzo RA, Abdul Ghani MA.Diabetes Care. 2011 Feb 25. Epub ahead of print. The study objective was to assess the relationship between β-cell function and HbA(1c).

Low-dose combination therapy with rosiglitazone and metformin to prevent type 2 diabetes mellitus (CANOE trial): a double-blind randomised controlled study

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Zinman B, Harris SB, Neuman J, Gerstein HC, Retnakaran RR, Raboud J, Qi Y, Hanley AJ. Low-dose combination therapy with rosiglitazone and metformin to prevent type 2 diabetes mellitus (CANOE trial): a double-blind randomised controlled study. Lancet. 2010;376(9735):103-111. The evolving epidemic of type 2 diabetes has challenged health-care providers to assess the safety and efficacy of various diabetes prevention strategies. The CANOE (CAnadian Normoglycemia Outcomes Evaluation) trial investigated whether low-dose combination therapy would affect development of type 2 diabetes.

Treatment of type 2 diabetes with glucagon-like peptide-1 receptor agonists

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Hansen KB, Knop FK, Holst JJ, Vilsbøll T. Treatment of type 2 diabetes with glucagon-like peptide-1 receptor agonists. Int J Clin Pract. 2009;63(8):1154-1160. The incretin system is an area of great interest for the development of new therapies for the management of type 2 diabetes. Existing antidiabetic drugs are often insufficient at getting patients to glycaemic goals.

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Slide Library Results

Search Results for: Pancreas Slides Found: 9
Energy Balance: Molecules That Regulate Eating and Energy Expenditure
Energy Balance: Molecules That Regulate Eating and Energy Expenditure (cont’d)
Plasticity of Islets: Experimental Increase in Beta-Cell Mass in Response to IR
Altered beta-Cell Mass and Function in Islets From Subjects With Type 2 Diabetes
Amyloid Deposits in Pancreatic Islets in Type 2 Diabetes
Medical Comorbidities Associated with Obesity
Incretin Therapies Vs Sulfonylureas Pancreatitis Type 2 Diabetes | NDEI
Beta-Cell Replacement ADA Type 1 Diabetes Guidelines | NDEI
Diabetes Comorbities ADA Guidelines | NDEI PPT