Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes

Monnier L, Mas E, Ginet C, Michel F, Villon L, Cristol JP, Colette C 

CONTEXT: Glycemic disorders, one of the main risk factors for cardiovascular disease, are associated with activation of oxidative stress. OBJECTIVE: To assess the respective contributions of sustained chronic hyperglycemia and of acute glucose fluctuations to oxidative stress in type 2 diabetes. (more) 

 


Monnier L, Mas E, Ginet C, et al. Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes. JAMA. 2006;295:1681-1687. 

03/2011
Last Modified: 12/12/2012