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Efficacy and Safety of Pioglitazone Plus Metformin
Einhorn D, Rendell M, Rosenzweig J, Egan JW, Mathisen AL, Schneider RL

A 16-week, double-blind study was conducted to determine the efficacy and tolerability of the combination of pioglitazone and metformin in the treatment of poorly controlled type 2 diabetes (HbA_1c>8.0%) in patients who had been on a stable dose of metformin for at least one month.  (more)

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Efficacy and Safety of Pioglitazone Plus a Sulfonylurea Dose-Response Effect of Pioglitazone on Insulin Sensitivity and Insulin Secretion in Type 2 Diabetes The Overall Results of Published US Clinical Trials of Pioglitazone Are Reviewed In Obese Rats, Pioglitazone Improves Glucose Metabolism and Insulin Sensitivity Primarily by Stimulating Energy Storage in Adipose Tissue Pioglitazone Hydrochloride Monotherapy Improves Glycemic Control in the Treatment of Patients With Type 2 Diabetes Pioglitazone in Type 2 Diabetes Poorly Controlled With a-Glucosidase Inhibitors, Alone or in Combination With Sulfonylureas Efficacy of Glyburide/Metformin Tablets Compared with Initial Monotherapy in Type 2 Diabetes Effect of Pioglitazone and Metformin on Insulin Sensitivity in Drug-Naïve Patients With Type 2 Diabetes Effect of Pioglitazone and Metformin on Glucose Control in Drug-Naïve Patients With Type 2 Diabetes One-Year Glycemic Control With a Sulfonylurea Plus Pioglitazone Versus a Sulfonylurea Plus Metformin in Patients With Type 2 Diabetes