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The formation of atheromatous lesions in the arterial intima.

The following content matched the glossary term: Atherogenesis

Evidence for a potent antiinflammatory effect of rosiglitazone


Mohanty P, Aljada A, Ghanim H, Hofmeyer D, Tripathy D, Syed T, Al-Haddad W, Dhindsa S, Dandona P. Evidence for a potent antiinflammatory effect of rosiglitazone. J Clin Endocrinol Metab. 2004;89:2728-2735. We have recently demonstrated a potent antiinflammatory effect of troglitazone, an agonist of peroxisome proliferator-activated receptor gamma (PPAR-gamma) and a partial agonist of PPAR-alpha in both the nondiabetic obese and diabetic obese subjects.

Management of Dyslipidemia in Children and Adolescents With Diabetes


American Diabetes Association. Management of Dyslipidemia in Children and Adolescents With Diabetes. Diabetes Care. 2003;26:2194-2197. Many studies have demonstrated that the atherosclerotic process begins in childhood in association with high blood cholesterol levels. Lipid levels show a strong familial aggregation that has both a genetic and environmental component.

Minireview: Adiposity, Inflammation, and Atherogenesis


Lyon CJ, Law RE, Hsueh WA. Minireview: Adiposity, Inflammation, and Atherogenesis. Endocrinology. 2003;144:2195-2200. Adipose tissue is a dynamic endocrine organ that secretes a number of factors that are increasingly recognized to contribute to systemic and vascular inflammation. 

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